I've been messing around with Tuneup disabling even more programs and I turned on more options to show a better display of what they do for pc load in regards to startup, shutdown, etc. This is where I'm at now:
I'm trying to decide on a few of the other things like the HP Quick Launch buttons and MS Office. I actually disabled the Apple Mobile Service but then couldn't connect my iPod as iTunes would no longer recognize it so I had to turn it back on. The one that makes a huge impact is Acronis. Look at the impact:
I have considered doing what I used to do and turn it off until I want to make a backup and then just enable it since I don't currently run it on any schedule. I'm actually trying to decide if it's of any benefit to keep some older backups I made from 09 which at this point I think are safe to remove. I have more current from this year anyway. Just one would save me just under 50GB on my secondary drive. Plus I have the backups that windows itself makes that I could also ditch and just use Acronis from here out. That would limit my secondary drive to 1 backup that just gets updated however often and my entire iTunes library. I would still have about the same amount of space used as I do now but it would be less intensive during a scheduled defrag.
I haven't really installed much new on this in recent times(the last few months) other than MSE back when it was released, Easeus Partition Master, PefectDisk 11 and the update to Tuneup Utilities 2011. I did install some MP3 converter but that is minor compared to the others.